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1

Simultaneous estimation of six anti-diabetic drugs—glibenclamide, gliclazide, glipizide, pioglitazone, repaglinide and rosiglitazone: development of a novel HPLC method for use in the analysis of pharmaceutical formulations and its application to human plasma assay

P. Venkatesh, T. Harisudhan, Hira Choudhury, Ramesh Mullangi, Nuggehally R. Srinivas

Journal:

Biomedical Chromatography

Year:

2006

Language:

english

File:

PDF, 169 KB

english, 2006

2

Clopidogrel: review of bioanalytical methods, pharmacokinetics/pharmacodynamics, and update on recent trends in drug–drug interaction studies

Ramesh Mullangi, Nuggehally R. Srinivas

Journal:

Biomedical Chromatography

Year:

2009

Language:

english

File:

PDF, 196 KB

english, 2009

3

Area under the curve predictions of dalbavancin, a new lipoglycopeptide agent, using the end of intravenous infusion concentration data point by regression analyses such as linear, log-linear and power models

Bhamidipati, Ravi Kanth, Syed, Muzeeb, Mullangi, Ramesh, Srinivas, Nuggehally

Journal:

Year:

2017

Language:

english

File:

PDF, 1.01 MB

english, 2017

4

Two Decades-Long Journey from Riluzole to Edaravone: Revisiting the Clinical Pharmacokinetics of the Only Two Amyotrophic Lateral Sclerosis Therapeutics

Dash, Ranjeet Prasad, Babu, R. Jayachandra, Srinivas, Nuggehally R.

Journal:

Clinical Pharmacokinetics

Year:

2018

Language:

english

File:

PDF, 1.15 MB

english, 2018

5

Standard curve range for clinical sample analysis of oral bioavailability/bioequivalence studies: dilemma, introspection and strategies

Tripathi, Prashant, Patel, Harilal, Kulshrestha, Tanuja, Srinivas, Nuggehally R

Journal:

Year:

2018

Language:

english

File:

PDF, 347 KB

english, 2018

6

Bioanalytical methods for the determination of itraconazole and hydroxyitraconazole: overview from clinical pharmacology, pharmacokinetic, pharmacodynamic and metabolism perspectives

Ming Yao, Nuggehally R. Srinivas

Journal:

Biomedical Chromatography

Year:

2009

Language:

english

File:

PDF, 197 KB

english, 2009

7

A rapid and highly sensitive method for the determination of glimepiride in human plasma by liquid chromatography–electrospray ionization tandem mass spectrometry: application to a pre-clinical pharmacokinetic study

Lagishetty Chakradhar, Rajareddy Kallem, Arumugam Karthik, Bala Tripura Sundari, Srirangam Ramesh, Ramesh Mullangi, Nuggehally R. Srinivas

Journal:

Biomedical Chromatography

Year:

2008

Language:

english

File:

PDF, 202 KB

english, 2008

8

Simultaneous quantitation of d7-nefazodone, nefazodone, d7-hydroxynefazodone, hydroxynefazodone, m-chlorophenylpiperazine and triazole-dione in human plasma by liquid chromatographic-mass spectrometry

Ming Yao, Nuggehally R. Srinivas

Journal:

Biomedical Chromatography

Year:

2000

Language:

english

File:

PDF, 102 KB

english, 2000

9

In vitro protein binding studies with BMS-204352: lack of protein binding displacement interaction in human serum

Rajesh Krishna, Ming Yao, Donna Kaczor, Nimish Vachharajani, Nuggehally R. Srinivas

Journal:

Biopharmaceutics & Drug Disposition

Year:

2001

Language:

english

File:

PDF, 52 KB

english, 2001

10

Niacin and its metabolites: role of LC-MS/MS bioanalytical methods and update on clinical pharmacology. An overview

Ramesh Mullangi, Nuggehally R Srinivas

Journal:

Biomedical Chromatography

Year:

2011

Language:

english

File:

PDF, 741 KB

english, 2011

11

An overview of various validated HPLC and LC-MS/MS methods for quantitation of drugs in bile: challenges and considerations

Nuggehally R. Srinivas, Ramesh Mullangi

Journal:

Biomedical Chromatography

Year:

2011

Language:

english

File:

PDF, 647 KB

english, 2011

12

Dealing with matrix effect: should there be a cut-off limit for signal ion suppression in quantitative assay validation?

Nuggehally R. Srinivas

Journal:

Biomedical Chromatography

Year:

2011

Language:

english

File:

PDF, 62 KB

english, 2011

13

Simultaneous determination of rosuvastatin and fenofibric acid in human plasma by LC–MS/MS with electrospray ionization: Assay development, validation and application to a clinical study

Ravi Kumar Trivedi, Raja Reddy Kallem, Ramesh Mullangi, Nuggehally R. Srinivas

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2005

Language:

english

File:

PDF, 263 KB

english, 2005

14

Rationale for faster oral delivery to overcome the pathophysiology associated with dental pain — Biopharmaceutic and pharmacokinetic challenges

Nuggehally R. Srinivas

Journal:

European Journal of Drug Metabolism and Pharmacokinetics

Year:

2009

Language:

english

File:

PDF, 496 KB

english, 2009

15

Enantioselective pharmacokinetics and pharmacodynamics of dl-thero-mcthylphenidate in children with attention deficit hyperactivity disorder

Srinivas, Nuggehally R, Hubbard, John W, Quinn, Declan, Midha, Kamal K

Journal:

Clinical Pharmacology & Therapeutics

Year:

1992

Language:

english

File:

PDF, 1.09 MB

english, 1992

16

Review of HPLC methods and HPLC methods with mass spectrometric detection for direct determination of aspirin with its metabolite(s) in various biological matrices

Ramesh Mullangi, Kuldeep Sharma, Nuggehally R. Srinivas

Journal:

Biomedical Chromatography

Year:

2012

Language:

english

File:

PDF, 387 KB

english, 2012

17

Quantification of fexofenadine in biological matrices: a review of bioanalytical methods

Ming Yao, Nuggehally R. Srinivas

Journal:

Biomedical Chromatography

Year:

2012

Language:

english

File:

PDF, 292 KB

english, 2012

18

Digoxin – a therapeutic agent and mechanistic probe: review of liquid chromatographic mass spectrometric methods and recent nuances in the clinical pharmacology attributes of digoxin

Srinivas, Nuggehally R, Ramesh, Mullangi

Journal:

Year:

2009

Language:

english

File:

PDF, 1.63 MB

english, 2009

19

Phenylephrine Pharmacokinetics and First-Pass Metabolism: What Is an Ideal Pharmacokinetic Surrogate?

Srinivas, Nuggehally R.

Journal:

Clinical Drug Investigation

Year:

2015

Language:

english

File:

PDF, 380 KB

english, 2015

20

First-in-human assays: excitement and introspection

Srinivas, Nuggehally R

Journal:

Year:

2009

Language:

english

File:

PDF, 668 KB

english, 2009

21

Erratum to: Phenylephrine Pharmacokinetics and First-Pass Metabolism: What Is an Ideal Pharmacokinetic Surrogate?

Srinivas, Nuggehally R.

Journal:

Clinical Drug Investigation

Year:

2015

Language:

english

File:

PDF, 330 KB

english, 2015

22

Therapeutic drug monitoring of cyclosporine and area under the curve prediction using a single time point strategy: appraisal using peak concentration data

Srinivas, Nuggehally R.

Journal:

Biopharmaceutics & Drug Disposition

Year:

2015

Language:

english

File:

PDF, 195 KB

english, 2015

23

Differences in the Prediction of Area Under the Curve for a Protease Inhibitor Using Trough Versus Peak Concentration

Srinivas, Nuggehally R.

Journal:

American Journal of Therapeutics

Year:

2015

Language:

english

File:

PDF, 275 KB

english, 2015

24

Strategy for the Prediction of Steady-State Exposure of Digoxin to Determine Drug–Drug Interaction Potential of Digoxin With Other Drugs in Digitalization Therapy

Srinivas, Nuggehally R.

Journal:

American Journal of Therapeutics

Year:

2016

Language:

english

File:

PDF, 484 KB

english, 2016

25

Review of the bioanalytical methods for the determination of methotrexate and its metabolites in in vitro, preclinical and clinical studies: case studies and perspectives

Patel, Harilal, Giri, Poonam, Ghoghar, Ashok, Delvadia, Prashant, Syed, Muzeeb, Srinivas, Nuggehally R.

Journal:

Biomedical Chromatography

Year:

2016

Language:

english

File:

PDF, 954 KB

english, 2016

26

Comparative pharmacokinetics of three SGLT-2 inhibitors sergliflozin, remogliflozin and ertugliflozin: An overview

Dash, Ranjeet Prasad, Babu, R. Jayachandra, Srinivas, Nuggehally R.

Journal:

Year:

2016

Language:

english

File:

PDF, 879 KB

english, 2016

27

Comment on: “Modeling the Relationship between Exposure to Abiraterone and Prostate-Specific Antigen Dynamics in Patients with Metastatic Castration-Resistant Prostate Cancer”

Srinivas, Nuggehally R.

Journal:

Clinical Pharmacokinetics

Year:

2017

Language:

english

File:

PDF, 354 KB

english, 2017

28

Influence of acute and chronic kidney failure in rats on the disposition and pharmacokinetics of ZYAN1, a novel prolyl hydroxylase inhibitor, for the treatment of chronic kidney disease-induced anemia

Patel, Harilal, Joharapurkar, Amit Arvind, Pandya, Vrajesh Bhaskarbhai, Patel, Vishal Jagjivanbhai, Kshirsagar, Samadhan Govind, Patel, Prakash, Gevriya, Bhavesh, Jain, Mukul R., Srinivas, Nuggehally

Journal:

Year:

2017

Language:

english

File:

PDF, 822 KB

english, 2017

29

A sensitive quantitative assay for the determination of propafenone and two metabolites, 5-hydroxypropafenone and N-depropylpropafenone, in human K2EDTA plasma using LC-MS/MS with ESI operated in a positive mode

Patel, Harilal, Ghoghari, Ashok, Bhatt, Chandrakant, Shah, Shaival, Jha, Anilkumar, Desai, Nirmal, Srinivas, Nuggehally R.

Journal:

Biomedical Chromatography

Year:

2017

Language:

english

File:

PDF, 1.86 MB

english, 2017

30

Sensitive LC-MS/MS Method for the Simultaneous Determination of Bendamustine and its Active Metabolite, γ-Hydroxybendamustine in Small Volume Mice and Dog Plasma and its Application to a Pharmacokinetic Study in Mice and Dogs

Chandrashekar, Devaraj, Suresh, Ponnayyan, Kumar, Rajnish, Bhamidipati, Ravi, Mullangi, Ramesh, Richter, Wolfgang, Srinivas, Nuggehally

Journal:

Year:

2017

Language:

english

File:

PDF, 890 KB

english, 2017

31

A sensitive assay for ZYAN1 in human whole blood and urine utilizing positive LC–MS/MS electrospray ionization

Patel, Harilal, Soni, Krunal, Trivedi, Rucha, Heading, Heather, Geue, Jason, Kansagra, Kevinkumar, Gupta, Rahul J, Pandya, Vrajesh B, Srinivas, Nuggehally R, Patel, Pankaj R, Desai, Ranjit C

Journal:

Year:

2017

Language:

english

File:

PDF, 1.96 MB

english, 2017

32

Preclinical evaluation of Saroglitazar Magnesium, a dual PPAR-α/γ agonist for treatment of dyslipidemia and metabolic disorders

Patel, Harilal, Giri, Poonam, Patel, Prakash, Singh, Sanjay, Gupta, Laxmikant, Patel, Urvesh, Modi, Nirav, Shah, Kalpesh, Jain, Mukul R, Srinivas, Nuggehally R., Patel, Pankaj

Journal:

Year:

2017

Language:

english

File:

PDF, 1.01 MB

english, 2017

33

Prediction of Human Pharmacokinetics of Bendamustine from Preclinical Species Pharmacokinetics Based on Normalizing Time Course Profiles

Jairam, Ravi, Mallurwar, Sadanand, Sulochana, Suresh, Chandrasekar, Devaraj, Bhamidipati, Ravi, Richter, Wolfgang, Srinivas, Nuggehally, Mullangi, Ramesh

Journal:

Year:

2018

Language:

english

File:

PDF, 499 KB

english, 2018

34

Cranberry Juice Ingestion and Clinical Drug-Drug Interaction Potentials; Review of Case Studies and Perspectives

Srinivas, Nuggehally R

Journal:

Journal of Pharmacy and Pharmaceutical Sciences

Year:

2013

File:

PDF, 334 KB

2013

35

Stereoselective pharmacokinetics and tissue distribution of levodropropizine after administration of pure levodropropizine and the rac -dropropizine to Sprague Dawley rats

Gabani, Bhavesh Babulal, Todmal, Umesh, Saini, Neeraj Kumar, Balakrishna, Vinod A, Sulochana, Suresh P, T, Ashok, Mohd, Zainuddin, Narayan, Balaji, Praharaj, Shuvranshu, Nuggehally, R Srinivas, Mullan

Journal:

Year:

2019

Language:

english

File:

PDF, 775 KB

english, 2019

36

Stereoselective Pharmacokinetic Disposition of Ketorolac Following Drug Administration to Periarticular Tissues in Patients

Srinivas, Nuggehally R.

Journal:

Anesthesia & Analgesia

Year:

2020

File:

PDF, 218 KB

2020

37

âTogether we move a mountainâ: celebrating a decade of the Emerging Voices for Global Health network

Srinivas, Prashanth Nuggehalli, Henriksson, Dorcus Kiwanuka, S Gordeev, Vladimir, Decoster, Kristof, Topp, Stephanie M, Abimbola, Seye

Journal:

BMJ Global Health

Year:

2020

File:

PDF, 312 KB

2020

38

Whole blood or plasma: what is the ideal matrix for pharmacokinetic-driven drug candidate selection?

PÂ Dash, Ranjeet, Veeravalli, Vijayabhaskar, AÂ Thomas, Jennifer, Rosenfeld, Clint, Mehta, Nirali, RÂ Srinivas, Nuggehally

Journal:

Future Medicinal Chemistry

Year:

2020

File:

PDF, 634 KB

2020

39

Effect of temperature on the high-performance liquid chromatographic separation of the anti-HIV agents, didanosine and stavudine

Frank A. Stancato, Nuggehally R. Srinivas, Catherine A. Knupp

Journal:

Biomedical Chromatography

Year:

1996

Language:

english

File:

PDF, 204 KB

english, 1996

40

Sensitive triple-quadrupole mass spectrometric assay for the determination of BMS-181885, a 5-HT1 agonist, in human plasma following solid phase extraction

Shu-Ying Chang, Daisy Whigan, Wen Chyi Shyu, Nuggehally R. Srinivas

Journal:

Biomedical Chromatography

Year:

1999

Language:

english

File:

PDF, 68 KB

english, 1999

41

Lack of effect of food on the steady state pharmacokinetics of BMS-181101, an antidepressant, in healthy subjects

Nuggehally R. Srinivas, Wen C. Shyu, James Lee, Douglas S. Greene, Rashmi H. Barbhaiya

Journal:

Biopharmaceutics & Drug Disposition

Year:

1997

Language:

english

File:

PDF, 128 KB

english, 1997

42

Pharmacokinetics and dose proportionality of BMS-204352 after intravenous administration to dogs

Rajesh Krishna, Vinod R. Shah, Subbaro Mantha, Nimish N. Vachharajani, Nuggehally Srinivas

Journal:

Biopharmaceutics & Drug Disposition

Year:

2002

Language:

english

File:

PDF, 66 KB

english, 2002

43

Disposition of radiolabeled BMS-204352 in rats and dogs

Rajesh Krishna, Ming Yao, Nuggehally R. Srinivas, Vinod Shah, Janice M. Pursley, Mark Arnold, Nimish N. Vachharajani

Journal:

Biopharmaceutics & Drug Disposition

Year:

2002

Language:

english

File:

PDF, 80 KB

english, 2002

44

Pharmacological and pharmacokinetic evaluation of celecoxib prodrugs in rats

Rao N.V.S. Mamidi, Ramesh Mullangi, Jagannath Kota, Ravikanth Bhamidipati, Ansar A. Khan, Kasiram Katneni, Srinivasaraju Datla, Sunil K. Singh, Koteswar Y. Rao, C. Seshagiri Rao, Nuggehally R. Sriniva

Journal:

Biopharmaceutics & Drug Disposition

Year:

2002

Language:

english

File:

PDF, 137 KB

english, 2002

45

Pharmacokinetics and dose proportionality of BMS-204352 after intraarterial administration to rats

Rajesh Krishna, Vinod R. Shah, Nuggehally Srinivas

Journal:

Biopharmaceutics & Drug Disposition

Year:

2002

Language:

english

File:

PDF, 73 KB

english, 2002

46

Effect of dose and input rate on the brain penetration of BMS-204352 following intravenous administration to rats

Rajesh Krishna, Holly Palme, Jianing Zeng, Nuggehally Srinivas

Journal:

Biopharmaceutics & Drug Disposition

Year:

2002

Language:

english

File:

PDF, 70 KB

english, 2002

47

Intravenous pharmacokinetics, oral bioavailability and dose proportionality of ragaglitazar, a novel PPAR-dual activator in rats

Kota Jagannath, Madhusudana Rao Chaluvadi, Ramesh Mullangi, N.V.S. Rao Mamidi, Nuggehally R. Srinivas

Journal:

Biopharmaceutics & Drug Disposition

Year:

2004

Language:

english

File:

PDF, 88 KB

english, 2004

48

Assessment of dose proportionality of muraglitazar after repeated oral dosing in rats via a sparse sampling methodology

Ming Yao, Arun Swaminathan, Nuggehally Srinivas

Journal:

Biopharmaceutics & Drug Disposition

Year:

2007

Language:

english

File:

PDF, 119 KB

english, 2007

49

Assessment of bioequivalence of drug racemates: what are the cues from a bioanalytical perspective—stereoselective vs nonstereoselective?

Nuggehally R Srinivas

Journal:

Biomedical Chromatography

Year:

2008

Language:

english

File:

PDF, 52 KB

english, 2008

50

Applicability of nonlinear calibration regression for quantitative determination of parent and metabolite(s) in bioequivalence assessment

Nuggehally R. Srinivas

Journal:

Biomedical Chromatography

Year:

2008

Language:

english

File:

PDF, 52 KB

english, 2008

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